Bromine → 2-Bromo-1-(4-bromo-2-methoxyphenyl)ethanone
Reaktionsgleichung
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:10])[CH3:9])=[C:4]([O:11][CH3:12])[CH:3]=1.[Br:13]Br>O1CCOCC1>[Br:13][CH2:9][C:8]([C:5]1[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][C:4]=1[O:11][CH3:12])=[O:10]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a stirred solution of 1-(4-bromo-2-methoxyphenyl)-1-ethanone (31.5 g, 138 mmol) in dioxane (32 ml) was added a solution of bromine (21.8 g, 136 mmol) in dioxane (123 ml), and the mixture was stirred for 3 hours. Then the volatile was evaporated in vacuo. The residue was recystallized with hexane-dichloromethane to give title compound (32.1 g, 76% yield).
Aufarbeitung
- customThen the volatile was evaporated in vacuo
Quellen und Nachweise
- ORD-Eintrag
- ord-ad954ee00a284514ab703d84a54b2ce6
- Quelldatensatz
- uspto-grants-2004_04
- Patentnummer
- US06727238B2
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