Stannous Chloride → 1-methyl-1H-1,2,3-benzotriazol-5-amine
Reaktionsgleichung
[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([N+:11]([O-])=O)=[CH:10][C:5]=2[N:4]=[N:3]1.Cl[Sn]Cl>Cl>[NH2:11][C:9]1[CH:8]=[CH:7][C:6]2[N:2]([CH3:1])[N:3]=[N:4][C:5]=2[CH:10]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
1-Methyl-5-nitrobenzotriazole (0.7 g) was reduced by SnCl2 (4.0 g) at 0° C. in 5 mL of conc. HCl. The pH of the reaction mixture was adjusted to basic and the mixture was extracted with EtOAc. The product 5-amino-1-methylbenzotriazole (0.4 g) obtained after removal of the solvent was used for the next reaction without further purification.
Aufarbeitung
- extractionwas extracted with EtOAc
Quellen und Nachweise
- ORD-Eintrag
- ord-618aa8567c664f0697fa0b745555645a
- Quelldatensatz
- uspto-grants-2013_05
- Patentnummer
- US08445694B2
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