2-Methyl-4-nitrobenzamide → 4-Amino-2-methylbenzamide
Reaktionsgleichung
[CH3:1][C:2]1[CH:10]=[C:9]([N+:11]([O-])=O)[CH:8]=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5]>CCO.[Pd]>[NH2:11][C:9]1[CH:8]=[CH:7][C:3]([C:4]([NH2:6])=[O:5])=[C:2]([CH3:1])[CH:10]=1Komponenten
4
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
2-methyl-4-nitrobenzamide (E111) was dissolved in EtOH under Ar and 10% Pd/C added. The reaction was pump-purged with H2 and left stirring at room temperature overnight. The catalyst was removed by filtration and the reaction concentrated to give pure 4-amino-2-methylbenzamide (E112).
Aufarbeitung
- additionadded
- customThe reaction was pump-purged with H2
- waitleft
- customThe catalyst was removed by filtration
- concentrationthe reaction concentrated
Quellen und Nachweise
- ORD-Eintrag
- ord-2b7bfc1b799b43cbba8ef60085ebdd41
- Quelldatensatz
- uspto-grants-2013_05
- Patentnummer
- US08450344B2
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