5-Phenyl-4-pentyn-1-ol → 4-Pentynal, 5-phenyl-

HRID 2106855Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2106855
[C:1]1([C:7]#[C:8][CH2:9][CH2:10][CH2:11][OH:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>C(Cl)Cl.CCOCC>[C:1]1([C:7]#[C:8][CH2:9][CH2:10][CH:11]=[O:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Komponenten

5

Edukt 2

HCID 111374345-Phenyl-4-pentyn-1-olHCID 178418287HCID 178418287, Verbindung

Produkt 1

HCID 112406334-Pentynal, 5-phenyl-

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 3283Diethyl EtherLösungsmittelHCID 6344DichloromethaneLösungsmittel2×

Versuchsvorschrift

A solution of 5-phenylpent-4-yn-1-ol (250 mg) in dry CH2Cl2 (2 ml) was added to a suspension of pyridinium chlorochromate (520 mg) in dry CH2Cl2 (3 ml). The mixture was stirred for 2.5 hours and diluted with ether, and the organic solution was decanted off. The oily residue was treated with ether (5×20 ml) and the extracts were washed successively with 5% NaHCO3, water and brine. After drying, the solvent was removed to yield 5-phenylpent-4-ynal.

Aufarbeitung

  1. customthe organic solution was decanted off
  2. additionThe oily residue was treated with ether (5×20 ml)
  3. washthe extracts were washed successively with 5% NaHCO3, water and brine
  4. customAfter drying
  5. customthe solvent was removed

Quellen und Nachweise

ORD-Eintrag
ord-fabfe7c25191416990009946db6b4e9a
Quelldatensatz
uspto-grants-1990_06
Patentnummer
US04931469

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