Potassium Iodide → HCID 23045048, Verbindung

HRID 2108037Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2108037
Br[CH2:2][CH2:3][CH2:4][CH2:5][O:6][CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1.CC(=O)[CH2:17][C:18](=[O:20])[CH3:19].C(=O)([O-])[O-].[K+].[K+].[I-].[K+]>C(O)C.CCOCC>[N:10]1[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=1[CH2:8][CH2:7][O:6][CH2:5][CH2:4][CH2:3][CH2:2][CH2:17][C:18](=[O:20])[CH3:19]

Komponenten

7

Edukt 4

HCID 4875Potassium IodideHCID 11430Potassium CarbonateHCID 31261AcetylacetoneHCID 230450722-[2-(4-Bromobutoxy)ethyl]pyridine

Produkt 1

HCID 23045048HCID 23045048, VerbindungAusbeute 83,3 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 702EthanolLösungsmittelHCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

A mixture of 2-[2-[(4-bromobutyl)oxy]ethyl]pyridine (6.2 g), 2,4-pentanedione (3.61 g), potassium carbonate (4.75 g) and potassium iodide (3.95 g) in ethanol (125 ml) was stirred and heated overnight under reflux. The solids were removed by filtration and the filtrate evaporated to leave a dark brown semi-solid. Addition of ether (200 ml) and filtration of the solid produced a brown solution which was evaporated to give a brown oil (4.71 g). Purification by FCC eluting with ether-hexane (1:1→3:1) gave the title compound as a pale yellow oil (1.93 g).

Aufarbeitung

  1. temperatureheated overnight
  2. temperatureunder reflux
  3. customThe solids were removed by filtration
  4. customthe filtrate evaporated
  5. customto leave a dark brown semi-solid
  6. customproduced a brown solution which
  7. customwas evaporated

Quellen und Nachweise

ORD-Eintrag
ord-db34ccea9f4b4518acbcdfeabed8f586
Quelldatensatz
uspto-grants-1990_06
Patentnummer
US04937251

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