4,5-Dimethoxyphthalic acid → 5,6-Dimethoxy-1,3-dihydro-2-benzofuran-1,3-dione

HRID 2111616

Reaktionsgleichung

Reaktionsgleichung von HRID 2111616
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:14]([OH:16])=[O:15])[C:6](=[CH:10][C:11]=1[O:12][CH3:13])[C:7]([OH:9])=O>C(OC(=O)C)(=O)C>[CH3:13][O:12][C:11]1[CH:10]=[C:6]2[C:7](=[O:9])[O:16][C:14](=[O:15])[C:5]2=[CH:4][C:3]=1[O:2][CH3:1]

Komponenten

3

Edukt 1

HCID 2909884,5-Dimethoxyphthalic acid

Produkt 1

HCID 6103565,6-Dimethoxy-1,3-dihydro-2-benzofuran-1,3-dioneAusbeute 48 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7918Acetic AnhydrideLösungsmittel

Versuchsvorschrift

The product of above-mentioned (b) (4.1 g, 18 mmol) was heated under reflux in acetic anhydride (14 ml) for 10 minutes. The reaction solution was poured into ice-cold water, and extracted with chloroform. The organic layer was washed with an aqueous saturated sodium bicarbonate solution and then water, dried and concentrated under reduced pressure to give 1.8 g of the title compound.

Aufarbeitung

  1. additionThe reaction solution was poured into ice-cold water
  2. extractionextracted with chloroform
  3. washThe organic layer was washed with an aqueous saturated sodium bicarbonate solution
  4. dry with materialwater, dried
  5. concentrationconcentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-d9ad4222b2b14916aec932ed1497abd8
Quelldatensatz
uspto-grants-2009_04
Patentnummer
US07521451B2

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