4-(4-Fluoro-benzyl)-piperidine → HCID 178521791, Verbindung
Reaktionsgleichung
[SH:1][C:2]1[NH:3][C:4]2[CH:10]=[C:9]([NH:11][C:12](=[O:16])[C:13]([OH:15])=O)[CH:8]=[CH:7][C:5]=2[N:6]=1.[F:17][C:18]1[CH:30]=[CH:29][C:21]([CH2:22][CH:23]2[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]2)=[CH:20][CH:19]=1>C(OCC)C>[F:17][C:18]1[CH:19]=[CH:20][C:21]([CH2:22][CH:23]2[CH2:24][CH2:25][N:26]([C:13](=[O:15])[C:12]([NH:11][C:9]3[CH:8]=[CH:7][C:5]4[N:6]=[C:2]([SH:1])[NH:3][C:4]=4[CH:10]=3)=[O:16])[CH2:27][CH2:28]2)=[CH:29][CH:30]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
The title compound is prepared from N-(2-mercapto-3H-benzimidazol-5-yl)-oxalamic acid (Example 60b) and 4-(4-fluoro-benzyl)-piperidine according to the method described in Example 1c. Melting Point: 286-288° C. (diethylether)