Potassium Iodide → 1-Methyl-5-nitroquinolin-1-ium iodide

HRID 2117319Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2117319
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][CH:8]=[N:9]2)([O-:3])=[O:2].S(OC)(O[CH3:18])(=O)=O.[I-:21].[K+]>O>[I-:21].[CH3:18][N+:9]1[C:10]2[C:5](=[C:4]([N+:1]([O-:3])=[O:2])[CH:13]=[CH:12][CH:11]=2)[CH:6]=[CH:7][CH:8]=1

Komponenten

5

Edukt 3

HCID 4875Potassium IodideHCID 6497Dimethyl SulfateHCID 118295-Nitroquinoline

Produkt 1

HCID 124950501-Methyl-5-nitroquinolin-1-ium iodide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

5-Nitroquinoline (4 g, 30 mmol) was melted at 85° C., prior to addition of dimethyl sulfate (2.2 ml, 30 mmol), and the resulting mixture was stirred at this temperature for 1.5 hours. The yellow gel was dissolved in water (35 ml) and cooled to room temperature. A saturated aqueous solution of potassium iodide (7.63 g, 45.9 mmol) was added, and the resulting orange precipitate was filtered, washing the residue with chilled water. After drying under vacuum at 60° C., for 2 hours, the brick-red solid was used in the next step without purification.

Aufarbeitung

  1. filtrationthe resulting orange precipitate was filtered
  2. washwashing the residue with chilled water
  3. customAfter drying under vacuum at 60° C., for 2 hours
  4. customthe brick-red solid was used in the next step without purification

Quellen und Nachweise

ORD-Eintrag
ord-ec8fbf85c3ab4e498eea5f7341e343fd
Quelldatensatz
uspto-grants-2008_10
Patentnummer
US07442701B2

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