HCID 14203475, Verbindung → 2-(4-aminophenyl)-5,6-dihydro-4H-1,3,4-oxadiazin-5-one

HRID 2119128Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2119128
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[O:11][CH2:12][C:13](=[O:16])[NH:14][N:15]=2)=[CH:6][CH:5]=1)([O-])=O>C(OCC)(=O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([C:10]2[O:11][CH2:12][C:13](=[O:16])[NH:14][N:15]=2)=[CH:8][CH:9]=1

Komponenten

4

Edukt 1

HCID 14203475HCID 14203475, Verbindung

Produkt 1

HCID 147428442-(4-aminophenyl)-5,6-dihydro-4H-1,3,4-oxadiazin-5-one

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

A solution of 2-p-nitrophenyl-4H,6H-1,3,4-oxadiazin-5-one (Example 17; 2.2 g.) in ethyl acetate (250 ml.) was hydrogenated in the presence of a 5% palladium-on-charcoal catalyst at laboratory temperature and atmospheric pressure until 670 ml. of hydrogen has been absorbed. The mixture was filtered and the filtrate was evaporated to dryness. There was thus obtained as solid residue 2-p-aminophenyl-4H,6H-1,3,4-oxadiazin-5-one, m.p. 253°-255° C. (with decomposition).

Aufarbeitung

  1. customof hydrogen has been absorbed
  2. filtrationThe mixture was filtered
  3. customthe filtrate was evaporated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-b0f7db73b5ed48c1a1c0fef1756c3bee
Quelldatensatz
uspto-grants-1987_07
Patentnummer
US04683232

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