1-Acetylnaphthalene → 1-(Naphthalen-1-yl)ethanone oxime

HRID 2122100

Reaktionsgleichung

Reaktionsgleichung von HRID 2122100
[C:1]([C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=[CH:6][CH:5]=1)(=O)[CH3:2].Cl.[NH2:15][OH:16]>N1C=CC=CC=1>[C:1](=[N:15][OH:16])([C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=[CH:6][CH:5]=1)[CH3:2]

Komponenten

4

Edukt 2

HCID 136631-AcetylnaphthaleneHCID 443297Hydroxyamine hydrochloride

Produkt 1

HCID 3496811-(Naphthalen-1-yl)ethanone oximeAusbeute 65 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

In a 50 ml round-bottom flask, a mixture of acetonaphthone, hydroxylamine hydrochloride in pyridine was stirred, at room temperature under nitrogen blanket, for five days. The reaction mixture was then concentrated under vacuum to remove most of pyridine. The oil was then dissolved in dichloromethane. The product precipitated on standing. The product was obtained as a white solid in 65% yield.

Aufarbeitung

  1. concentrationThe reaction mixture was then concentrated under vacuum
  2. customto remove most of pyridine
  3. dissolutionThe oil was then dissolved in dichloromethane
  4. customThe product precipitated
  5. customThe product was obtained as a white solid in 65% yield

Quellen und Nachweise

ORD-Eintrag
ord-c499d1520b644d4698af39ebe86f5379
Quelldatensatz
uspto-grants-2004_02
Patentnummer
US06696608B1

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