Acetic Acid → 4-[3-((-)-4-Hydroxy-6-aza-spiro[2.5]oct-6-yl)-propyl]-5-oxo-[1,4]diazepane-1-carboxylic acid tert-butyl ester
Reaktionsgleichung
[BH3:30].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:16][CH2:17][CH:18]=[O:19])[C:12](=[O:15])[CH2:13][CH2:14]1.[C:37]([OH:38])(=[O:39])[CH3:40].[CH2:21]1[CH2:22][C:23]12[CH:24]([OH:29])[CH2:25][NH:26][CH2:27][CH2:28]2.[ClH:20].[n:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:16][CH2:17][CH2:18][N:26]2[CH2:25][CH:24]([OH:29])[C:23]3([CH2:21][CH2:22]3)[CH2:28][CH2:27]2)[C:12](=[O:15])[CH2:13][CH2:14]1
