Diethyl Ether → HCID 23462418, Verbindung
Reaktionsgleichung
[CH3:1][C:2]1[N:3]2[CH:9]=[C:8]([CH2:10]O)[N:7]=[C:4]2[S:5][CH:6]=1.CCOCC.O=S(Cl)[Cl:19]>>[ClH:19].[CH3:1][C:2]1[N:3]2[CH:9]=[C:8]([CH2:10][Cl:19])[N:7]=[C:4]2[S:5][CH:6]=1Komponenten
4
Versuchsvorschrift
10 g of 3-methyl-6-hydroxymethyl-imidazo-(2,1-b)thiazole prepared as described in one of the methods in Example 26, is refluxed for 2 hours in 100 ml of SOCl2. The solution is then cooled, 50 ml of ether are added to yield 11 g of 3-methyl-6-chloromethyl-imidazo-(2,1-b)thiazole hydrochloride; m.p. 280°.
Aufarbeitung
- temperatureThe solution is then cooled
Quellen und Nachweise
- ORD-Eintrag
- ord-4f2b1bb0ce124878a54aeb9667cba231
- Quelldatensatz
- uspto-grants-1979_01
- Patentnummer
- US04137320
Notizen zur Reaktion
Wird geladen…