Sulfuryl chloride → 2-Chloro-1-(3,5-di-tert-butyl-4-hydroxyphenyl)ethan-1-one

HRID 2165736Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2165736
S(Cl)([Cl:4])(=O)=O.[C:6]([C:10]1[CH:11]=[C:12]([C:21](=[O:23])[CH3:22])[CH:13]=[C:14]([C:17]([CH3:20])([CH3:19])[CH3:18])[C:15]=1[OH:16])([CH3:9])([CH3:8])[CH3:7]>C(Cl)Cl>[Cl:4][CH2:22][C:21]([C:12]1[CH:11]=[C:10]([C:6]([CH3:9])([CH3:7])[CH3:8])[C:15]([OH:16])=[C:14]([C:17]([CH3:20])([CH3:19])[CH3:18])[CH:13]=1)=[O:23]

Komponenten

4

Edukt 2

HCID 24648Sulfuryl chlorideHCID 6162963',5'-Bis(tert-butyl)-4'-hydroxyacetophenone

Produkt 1

HCID 142109772-Chloro-1-(3,5-di-tert-butyl-4-hydroxyphenyl)ethan-1-one

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel2×

Versuchsvorschrift

16.2 g (0.12 mol) of sulfuryl chloride in 50 ml of methylene chloride were added dropwise while stirring to a solution of 19.9 g (0.08 mol) of 1-(3,5-di-tert.butyl-4-hydroxyphenyl)-ethanone in 250 ml of methylene chloride at room temperature. After stirring for 3 hours at room temperature, the batch was washed by shaking first with water and then with a saturated sodium hydrogen carbonate solution, and the methylene chloride phase was dried over sodium sulfate and evaporated under reduced pressure.

Aufarbeitung

  1. washthe batch was washed
  2. stirringby shaking first with water
  3. dry with materialwith a saturated sodium hydrogen carbonate solution, and the methylene chloride phase was dried over sodium sulfate
  4. customevaporated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-76ee66c018ac4272baa47d8ba1f61b90
Quelldatensatz
uspto-grants-1990_07
Patentnummer
US04940790

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