Hydrochloric Acid → HCID 20062857, Verbindung

HRID 2166160Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2166160
Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][O:7][CH2:8][CH2:9][CH2:10][C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=1.[CH2:19]([NH2:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.[ClH:27]>O>[ClH:27].[CH3:18][O:17][C:14]1[CH:15]=[CH:16][C:11]([CH2:10][CH2:9][CH2:8][O:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][NH:26][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[CH:12][CH:13]=1

Komponenten

5

Edukt 3

HCID 313Hydrochloric AcidHCID 7504BenzylamineHCID 197980251-[3-[(5-Bromopentyl)oxy]propyl]-4-methoxybenzene

Produkt 1

HCID 20062857HCID 20062857, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

1-[3-[(5-Bromopentyl)oxy]propyl]-4-methoxybenzene (2.0 g) was added to benzylamine (6 ml) at 120° under nitrogen. The solution was stirred for 2 h at 120° then added (hot) to 2N hydrochloric acid (50 ml) and water (25 ml). The resulting precipitate was collected by filtration, washed with 2N hydrochloric acid, water and ER then dried at 50° under vacuum to give the title compound as a white solid (1.79 g) m.p. 118°-121°. The following compound was prepared in a similar manner:

Aufarbeitung

  1. filtrationThe resulting precipitate was collected by filtration
  2. washwashed with 2N hydrochloric acid, water and ER
  3. customthen dried at 50° under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-2c9325fea5a64b7eaecc18b92831e77b
Quelldatensatz
uspto-grants-1990_07
Patentnummer
US04943591

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