Benzenesulfonyl chloride → N'-t-butyl-N-benzenesulfonyl-N'-benzoylhydrazine

HRID 21668Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 21668
[C:1]([N:5]([C:7](=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[NH2:6])([CH3:4])([CH3:3])[CH3:2].[C:15]1([S:21](Cl)(=[O:23])=[O:22])[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>N1C=CC=CC=1.C(OCC)C>[C:1]([N:5]([C:7](=[O:14])[C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1)[NH:6][S:21]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)(=[O:23])=[O:22])([CH3:4])([CH3:2])[CH3:3]

Komponenten

5

Edukt 2

HCID 7369Benzenesulfonyl chlorideHCID 1275961N-(tert-butyl)benzohydrazide

Produkt 1

HCID 14623289N'-t-butyl-N-benzenesulfonyl-N'-benzoylhydrazine

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 1049PyridineLösungsmittelHCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

N'-t-butyl-N'-benzoylhydrazine (0.4 g) was stirred in pyridine (3 ml) at room temperature. Benzenesulfonyl chloride (0.5 g) was added slowly, dropwise and stirred for 2 hours, diluted with diethyl ether (20 ml) and washed several times with a 10% HCl solution and then water. The organic layer was dried over magnesium sulfate, filtered and the solvent rotavapped off to afford a white solid in good yield.

Aufarbeitung

  1. washwashed several times with a 10% HCl solution
  2. dry with materialThe organic layer was dried over magnesium sulfate
  3. filtrationfiltered
  4. customto afford a white solid in good yield

Quellen und Nachweise

ORD-Eintrag
ord-47782f9b5f06407a89236f994f00b2a5
Quelldatensatz
uspto-grants-1995_06
Patentnummer
US05424333

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