Carbon Dioxide → 2-(prop-2-yn-1-yl)pent-4-ynoic acid

Reaktionsgleichung

[CH2:1]([C:4]([CH2:11][C:12]#[CH:13])(C(O)=O)[C:5]([OH:7])=[O:6])[C:2]#[CH:3].C(=O)=O>>[CH2:1]([CH:4]([CH2:11][C:12]#[CH:13])[C:5]([OH:7])=[O:6])[C:2]#[CH:3]

Komponenten

Edukt 2

HCID 280Carbon Dioxide

HCID 12686700HCID 12686700, Verbindung

Produkt 1

HCID 136736532-(prop-2-yn-1-yl)pent-4-ynoic acidAusbeute 79,9 %

Versuchsvorschrift

The dipropargylmalonic acid (26 gm, 0.443 mol) was heated neat at 135 C until CO2 stopped evolving. It was then allowed to cool to an oil. The oil was distilled at 0.5 psi. The remaining oily residue in the distillation flask and solid were combined (15.7 gm, 79.9% yield) and was used as is in the next step.

Aufarbeitung

temperatureto cool to an oil
distillationThe oil was distilled at 0.5 psi

Quellen und Nachweise

ORD-Eintrag: ord-545cf4bbd49e4424a2f28d6a38257435
Quelldatensatz: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US09050370B2

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