Sodium Acetate → 3-Acetoxypropyltrivinylsilane

HRID 217567

Reaktionsgleichung

Reaktionsgleichung von HRID 217567
Cl[CH2:2][CH2:3][CH2:4][Si:5]([CH:10]=[CH2:11])([CH:8]=[CH2:9])[CH:6]=[CH2:7].[C:12]([O-:15])(=[O:14])[CH3:13].[Na+]>CN(C)C=O>[C:12]([O:15][CH2:2][CH2:3][CH2:4][Si:5]([CH:10]=[CH2:11])([CH:8]=[CH2:9])[CH:6]=[CH2:7])(=[O:14])[CH3:13]

Komponenten

4

Edukt 2

HCID 517045Sodium AcetateHCID 23630656Trivinyl(3-chloropropyl)silane

Produkt 1

HCID 579455963-AcetoxypropyltrivinylsilaneAusbeute 76 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Reaktionsbedingungen

Temperatur
120 °C

Versuchsvorschrift

As shown in Reaction Scheme 24, 3-chloropropyltrivinylsilane (1.0 g, 5.35 mmol) and sodium acetate (0.87 g, 10.7 mmol) were dissolved in 17 mL of dimethylformamide (DMF), and the reaction mixture was heated at 120° C. for 12 hours. After the reaction, the organic layer was separated after addition of distilled water and ether. The organic layer was dried over MgSO4, concentrated by evaporation of solvent, and the resulting residue was purified by column chromatography (n-Hex: EA=10:1, Rf=0.4) to give 855 mg (76% yield) of pure 3-acetoxypropyltrivinylsilane.

Aufarbeitung

  1. customAfter the reaction
  2. customthe organic layer was separated
  3. additionafter addition of distilled water and ether
  4. dry with materialThe organic layer was dried over MgSO4
  5. concentrationconcentrated by evaporation of solvent
  6. customthe resulting residue was purified by column chromatography (n-Hex: EA=10:1, Rf=0.4)

Quellen und Nachweise

ORD-Eintrag
ord-672dfd5c3911452085a6ee1da2c6cf62
Quelldatensatz
uspto-grants-2012_06
Patentnummer
US08197903B2

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