Hydrogen Bromide → 2-Amino-5-bromo-1H-pyrrole-3,4-dicarbonitrile

HRID 2175723Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2175723
[C:1]([C:3]([C:9]#[N:10])=[C:4]([C:7]#[N:8])[C:5]#[N:6])#[N:2].[BrH:11]>CC(C)=O.C(OCC)(=O)C.C(O)(=O)C>[NH2:2][C:1]1[NH:6][C:5]([Br:11])=[C:4]([C:7]#[N:8])[C:3]=1[C:9]#[N:10]

Komponenten

6

Edukt 2

HCID 260Hydrogen BromideHCID 12635Tetracyanoethylene

Produkt 1

HCID 6109782-Amino-5-bromo-1H-pyrrole-3,4-dicarbonitrileAusbeute 66,8 %

Reagenzien, Katalysatoren, Lösungsmittel 3

HCID 176Acetic AcidLösungsmittelHCID 180AcetoneLösungsmittelHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

Tetracyanoethylene (10.02 g, 78.23 mmol) was dissolved in the mixed solvent of acetone (60 mL) and ethyl acetate (120 mL), to which hydrogen bromide (33 wt %, 60 mL) dissolved in acetic acid was added at 0˜5° C. The yellow solid compound observed after one hour-stirring was isolated by filtering. After washing the compound with cold distilled water (100 mL), the mixture was dried in the air to give the target compound (11.02 g, 52.22 mmol, 66.8%).

Aufarbeitung

  1. additionwas added at 0˜5° C
  2. customwas isolated
  3. filtrationby filtering
  4. washAfter washing the compound
  5. distillationwith cold distilled water (100 mL)
  6. customthe mixture was dried in the air

Quellen und Nachweise

ORD-Eintrag
ord-d6d498be3d55433a8bde26539f9937fe
Quelldatensatz
uspto-grants-2015_06
Patentnummer
US09062088B2

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