HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-(Methylcarbamoyl)propanoic acid → (3aR,4S,7aR)-methyl 4-(4-(methylamino)-4-oxobutanoyloxy)-4-(m-tolylethynyl)octahydro-1H-indole-1-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-(Methylcarbamoyl)propanoic acid | HCID 292050 | — |
| Edukt | (3aS,4R,7aS)-4-hydroxy-4-m-tolylethynyl-octahydro-indole-1-carboxylic acid methyl ester | HCID 68276168 | — |
| Produkt | (3aR,4S,7aR)-methyl 4-(4-(methylamino)-4-oxobutanoyloxy)-4-(m-tolylethynyl)octahydro-1H-indole-1-carboxylate | HCID 86702180 | — |
Reaktionsschritte
Synthesis in analogy to the General Method 1 starting from (3aS,4R,7aS)-4-hydroxy-4-m-tolylethynyl-octahydro-indole-1-carboxylic acid methyl ester and N-methylsuccinamic acid to yield (3aR,4S,7aR)-methyl 4-(4-(methylamino)-4-oxobutanoyloxy)-4-(m-tolylethynyl)octahydro-1H-indole-1-carboxylate. MS [M+H]=427; RT=1.06 min; UPLC Method I
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09067881B2 |
| Quelldatensatz | uspto-grants-2015_06 |
| ORD ID | ord-dcf85e8d928040f58183a4343805165e |
| Quellennotiz | uspto-grants-2015_06 |