HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Potassium Carbonate → 3-Chloro-5-[(3-methoxyphenyl)sulfonyl]-6-methyl-5,6-dihydrophenanthridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | N-[1-(4'-chloro-2'-fluoro-1,1'-biphenyl-2-yl)ethyl]-3-methoxybenzenesulfonamide | HCID 22482365 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 3-Chloro-5-[(3-methoxyphenyl)sulfonyl]-6-methyl-5,6-dihydrophenanthridine | HCID 22482385 | — |
Reaktionsschritte
The title compound was prepared from N-[1-(4′-chloro-2′-fluoro-1,1′-biphenyl-2-yl)ethyl]-3-methoxybenzenesulfonamide (686 mg, 1.6 mmol), anhydrous N,N-dimethylformamide (2 mL), and potassium carbonate (442 mg, 3.2 mmol) according to the procedure and in the same manner as described in Example 105, step d resulting in the isolation of 547 mg (84%) of a white solid that was used without further purification;
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06894061B2 |
| Quelldatensatz | uspto-grants-2005_05 |
| ORD ID | ord-450d5ed9802d4dab8c945f1b05285d77 |
| Quellennotiz | uspto-grants-2005_05 |