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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2181928Erstellt: 26. Oktober 2026

Potassium Carbonate → 3-Chloro-5-[(3-methoxyphenyl)sulfonyl]-6-methyl-5,6-dihydrophenanthridine

https://huagongshe.com/reaction/2181928

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktPotassium CarbonateHCID 11430—
EduktN-[1-(4'-chloro-2'-fluoro-1,1'-biphenyl-2-yl)ethyl]-3-methoxybenzenesulfonamideHCID 22482365—
LösungsmittelDimethylformamideHCID 6228—
Produkt3-Chloro-5-[(3-methoxyphenyl)sulfonyl]-6-methyl-5,6-dihydrophenanthridineHCID 22482385—

Reaktionsschritte

The title compound was prepared from N-[1-(4′-chloro-2′-fluoro-1,1′-biphenyl-2-yl)ethyl]-3-methoxybenzenesulfonamide (686 mg, 1.6 mmol), anhydrous N,N-dimethylformamide (2 mL), and potassium carbonate (442 mg, 3.2 mmol) according to the procedure and in the same manner as described in Example 105, step d resulting in the isolation of 547 mg (84%) of a white solid that was used without further purification;

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06894061B2
Quelldatensatzuspto-grants-2005_05
ORD IDord-450d5ed9802d4dab8c945f1b05285d77
Quellennotizuspto-grants-2005_05