3-nitro-9-isopropyl-9H-carbazole → HCID 11790847, Verbindung

HRID 2184931Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2184931
[CH:1]([N:4]1[C:16]2[CH:15]=[CH:14][C:13]([N+:17]([O-])=O)=[CH:12][C:11]=2[C:10]2[C:5]1=[CH:6][CH:7]=[CH:8][CH:9]=2)([CH3:3])[CH3:2]>CCO.[Pd]>[CH:1]([N:4]1[C:16]2[CH:15]=[CH:14][C:13]([NH2:17])=[CH:12][C:11]=2[C:10]2[C:5]1=[CH:6][CH:7]=[CH:8][CH:9]=2)([CH3:3])[CH3:2]

Komponenten

4

Edukt 1

HCID 6174713-nitro-9-isopropyl-9H-carbazole

Produkt 1

HCID 11790847HCID 11790847, VerbindungAusbeute 98,4 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

To a solution of 9-Isopropyl-3-nitro-9H-carbazole(1.5 g, 5.89 mmol) in EtOH (100 ml) was added 10% Pd-C (150 mg) and the reaction mixture was hydrogenated with a Parr hydrogenation apparatus at 45 psi H2 pressure for 3 hours. The reaction mixture was filtered and the filtrate concentrated in vacuo to afford the desired product as a solid (1.3 g, 87%).

Aufarbeitung

  1. filtrationThe reaction mixture was filtered
  2. concentrationthe filtrate concentrated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-c589a92b2ef6434d939ce04e5de9da8e
Quelldatensatz
uspto-grants-2002_06
Patentnummer
US06399631B1

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