4-Chlorobenzaldehyde → 2-[(4-cyano-3-fluoro-phenyl)-hydroxy-methyl]-5-(2,4-dimethoxy-pyrimidin-5-yl)-1-isopropyl-1H-pyrrole-3-carboxylic acid methyl ester

Reaktionsgleichung

[CH3:1][O:2][C:3]([C:5]1[CH:9]=[C:8]([C:10]2[C:11]([O:18][CH3:19])=[N:12][C:13]([O:16][CH3:17])=[N:14][CH:15]=2)[N:7]([CH:20]([CH3:22])[CH3:21])[CH:6]=1)=[O:4].[F:23][C:24]1[CH:31]=[C:30]([CH:32]=[O:33])[CH:29]=[CH:28][C:25]=1[C:26]#[N:27].COC(C1C=C(Br)N(C(C)C)C=1)=O.ClC1C=CC(C=O)=CC=1>>[CH3:1][O:2][C:3]([C:5]1[CH:9]=[C:8]([C:10]2[C:11]([O:18][CH3:19])=[N:12][C:13]([O:16][CH3:17])=[N:14][CH:15]=2)[N:7]([CH:20]([CH3:22])[CH3:21])[C:6]=1[CH:32]([C:30]1[CH:29]=[CH:28][C:25]([C:26]#[N:27])=[C:24]([F:23])[CH:31]=1)[OH:33])=[O:4]