HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 220611Erstellt: 26. Oktober 2026
Acetic Acid → 2-chloro-8-methyl-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-11-one
https://huagongshe.com/reaction/220611
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Acetic Acid | HCID 176 | — |
| Edukt | 3,4-Diaminotoluene | HCID 10332 | — |
| Edukt | 5-chloro-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione | HCID 639058 | — |
| Produkt | 2-chloro-8-methyl-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-11-one | HCID 68718219 | — |
Reaktionsschritte
A mixture of 4-methyl-1,2-phenylenediamine (0.1 mol) and 6-chloro isatoic anhydride (0.1 mol) in acetic acid (85%) was heated at 110° C. for 2 hrs. The mixture was poured into ice-cold water and 2-chloro-8-methyl-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-11-one was isolated (93%) after neutralisation and filtration.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US08202989B2 |
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| Quelldatensatz | uspto-grants-2012_06 |
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| ORD ID | ord-54cc76e55d0f4c9294ad4d59f0331240 |
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| Quellennotiz | uspto-grants-2012_06 |
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