HCID 72548394, Verbindung → (S)-2-[2-(4-{[(2R,3S,4R,5S)-4-(4-chloro-2-fluoro-phenyl)-3-(3-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carbonyl]-amino}-3-methoxy-benzoyloxy)-acetylamino]-pentanedioic acid
Reaktionsgleichung
C([O:8][C:9](=[O:69])[C@@H:10]([NH:23][C:24](=[O:68])[CH2:25][O:26][C:27](=[O:67])[C:28]1[CH:33]=[CH:32][C:31]([NH:34][C:35]([C@H:37]2[C@H:41]([C:42]3[CH:47]=[CH:46][CH:45]=[C:44]([Cl:48])[C:43]=3[F:49])[C@:40]([C:52]3[CH:57]=[CH:56][C:55]([Cl:58])=[CH:54][C:53]=3[F:59])([C:50]#[N:51])[C@H:39]([CH2:60][C:61]([CH3:64])([CH3:63])[CH3:62])[NH:38]2)=[O:36])=[C:30]([O:65][CH3:66])[CH:29]=1)[CH2:11][CH2:12][C:13]([O:15]CC1C=CC=CC=1)=[O:14])C1C=CC=CC=1>[Pd].C(O)(C)C>[Cl:58][C:55]1[CH:56]=[CH:57][C:52]([C@@:40]2([C:50]#[N:51])[C@H:39]([CH2:60][C:61]([CH3:62])([CH3:64])[CH3:63])[NH:38][C@@H:37]([C:35]([NH:34][C:31]3[CH:32]=[CH:33][C:28]([C:27]([O:26][CH2:25][C:24]([NH:23][C@@H:10]([CH2:11][CH2:12][C:13]([OH:15])=[O:14])[C:9]([OH:69])=[O:8])=[O:68])=[O:67])=[CH:29][C:30]=3[O:65][CH3:66])=[O:36])[C@@H:41]2[C:42]2[CH:47]=[CH:46][CH:45]=[C:44]([Cl:48])[C:43]=2[F:49])=[C:53]([F:59])[CH:54]=1Komponenten
4
