3-(4-Hydroxymethylphenyl)acrylic acid ethyl ester → Ethyl 3-(4-(hydroxymethyl)phenyl)propanoate

HRID 2218118Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2218118
[CH2:1]([O:3][C:4](=[O:15])[CH:5]=[CH:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][OH:14])=[CH:9][CH:8]=1)[CH3:2].[H][H]>[Pd].C(O)C>[CH2:1]([O:3][C:4](=[O:15])[CH2:5][CH2:6][C:7]1[CH:8]=[CH:9][C:10]([CH2:13][OH:14])=[CH:11][CH:12]=1)[CH3:2]

Komponenten

5

Edukt 2

HCID 684575823-(4-Hydroxymethylphenyl)acrylic acid ethyl esterHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 14839455Ethyl 3-(4-(hydroxymethyl)phenyl)propanoate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

3-(4-Hydroxymethylphenyl)acrylic acid ethyl ester (P4, 3 g, 14.5 mmol) and palladium on charcoal (0.3 g) in ethanol (30 mL) was stirred for 4 hours under atmospheric pressure of hydrogen. The reaction mixture was filtered through celite (Diatomaceous Earth) and concentrated to afford the title compound as an oil.

Aufarbeitung

  1. filtrationThe reaction mixture was filtered through celite (Diatomaceous Earth)
  2. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-88962a19cc68445dac2f54de163f87b2
Quelldatensatz
uspto-grants-2008_08
Patentnummer
US07410984B2

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