3-benzyloxy-1-phenyl-1H-pyrazole-4-carbaldehyde → HCID 178519806, Verbindung
Reaktionsgleichung
C([O:8][C:9]1[C:13]([CH:14]=[O:15])=[CH:12][N:11]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[N:10]=1)C1C=CC=CC=1>[Pd].O1CCCC1>[OH:8][C:9]1[C:13]([CH:14]=[O:15])=[CH:12][N:11]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)[N:10]=1Komponenten
4
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
3-Benzyloxy-1-phenyl-1H-pyrazole-4-carbaldehyde (0.30 g), 5% palladium on carbon (0.50 g) and tetrahydrofuran (10 mL) were subjected to catalytic reduction under a hydrogen atmosphere and atmospheric pressure. The catalyst was filtered off and the filtrate was concentrated to give 3-hydroxy-1-phenyl-1H-pyrazole-4-carbaldehyde as colorless crystals (0.16 g, yield 76%). Recrystallization from ethyl acetate-hexane gave colorless prism crystals. melting point: 196-197° C.