Hydrochloric Acid → (4-(4-Methyl-3-pentenyl)-3-cyclohexenyl)acetic acid

HRID 2227099Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2227099
[OH-:1].[Na+].[CH3:3][C:4]([CH3:17])=[CH:5][CH2:6][CH2:7][C:8]1[CH2:13][CH2:12][CH:11]([CH2:14][C:15]#N)[CH2:10][CH:9]=1.Cl.[OH2:19]>OO>[CH3:3][C:4]([CH3:17])=[CH:5][CH2:6][CH2:7][C:8]1[CH2:13][CH2:12][CH:11]([CH2:14][C:15]([OH:19])=[O:1])[CH2:10][CH:9]=1

Komponenten

6

Edukt 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 14798Sodium HydroxideHCID 18471789(4-(4-Methyl-3-pentenyl)-3-cyclohexenyl)acetonitrile

Produkt 1

HCID 18471803(4-(4-Methyl-3-pentenyl)-3-cyclohexenyl)acetic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 784Hydrogen PeroxideLösungsmittel

Versuchsvorschrift

To a solution of sodium hydroxide (10.5 g) in water (150 mL) and 30% hydrogen peroxide (50 mL) is added the nitrile 2A (R=4-Methyl-3-pentenyl) (10 g). The reaction mixture is stirred at reflux overnight. The reaction is then cooled to room temperature, and poured into a mixture of ice (30 g) and hydrochloric acid (22 mL). The acid product is extracted with ethyl acetate, and the combined organic layers are washed with brine and dried over magnesium sulfate. The solution is concentrated in vacuo.

Aufarbeitung

  1. temperatureat reflux overnight
  2. extractionThe acid product is extracted with ethyl acetate
  3. washthe combined organic layers are washed with brine
  4. dry with materialdried over magnesium sulfate
  5. concentrationThe solution is concentrated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-653a52b5aaee4cd8bec4f76a400e3192
Quelldatensatz
uspto-grants-2002_07
Patentnummer
US06413448B1

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