Hydrazine hydrate (1:1) → 2-hydrazono-1-phenylpropan-1-one O-methyl oxime

HRID 2229132Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2229132
[CH3:1][O:2][N:3]=[C:4]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:5](=O)[CH3:6].O.[NH2:15][NH2:16]>C(O)C>[CH3:1][O:2][N:3]=[C:4]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:5](=[N:15][NH2:16])[CH3:6]

Komponenten

4

Edukt 2

HCID 24654Hydrazine hydrate (1:1)HCID 539446061-phenylpropane-1,2-dione 1-(O-methyl oxime)

Produkt 1

HCID 572718472-hydrazono-1-phenylpropan-1-one O-methyl oximeAusbeute 56 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

2.5 g (0.014 mol) of 1-phenylpropane-1,2-dione 1-(O-methyl oxime) are heated at 60° C. in 20 ml of ethanol with 1.45 g (0.029 mol) of hydrazine hydrate for 1 hour. The reaction mixture is poured onto water and extracted with diethyl ether, the organic phase is dried over sodium sulphate and the solvent is distilled off in vacuo. The residue is stirred with diethyl ether and the crystals are filtered off. 1.5 g (55.6% of theory) of 2-hydrazono-1-phenylpropan-1-one O-methyl oxime of melting point 132° C. are obtained.

Aufarbeitung

  1. additionThe reaction mixture is poured onto water
  2. extractionextracted with diethyl ether
  3. dry with materialthe organic phase is dried over sodium sulphate
  4. distillationthe solvent is distilled off in vacuo
  5. filtrationthe crystals are filtered off

Quellen und Nachweise

ORD-Eintrag
ord-f451d3764de9463eaa794004fca71fa6
Quelldatensatz
uspto-grants-2002_07
Patentnummer
US06420362B1

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