Hydrochloric Acid → 5-Aminoisothiazole-3,4-dicarbonitrile

HRID 2231960Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2231960
CN(C)C=[N:4][C:5]1[S:9][N:8]=[C:7]([C:10]#[N:11])[C:6]=1[C:12]#[N:13].C(O)C.Cl>O>[NH2:4][C:5]1[S:9][N:8]=[C:7]([C:10]#[N:11])[C:6]=1[C:12]#[N:13]

Komponenten

5

Edukt 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 54385684HCID 54385684, Verbindung

Produkt 1

HCID 212852515-Aminoisothiazole-3,4-dicarbonitrileAusbeute 87 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of 45.3 parts of N,N-dimethyl-N'-(3,4-dicyanoisothiazol-5-yl)-formamidine, 400 parts of ethanol and 60 parts of concentrated hydrochloric acid is heated at the boil for 2.5 hours, after which it is introduced into 400 parts of water. The colorless precipitate is filtered off under suction, washed with water and dried to give 28.6 parts (87% of theory) of 5-aminoisothiazole-3,4-dicarbonitrile.

Aufarbeitung

  1. temperatureis heated at the boil for 2.5 hours
  2. filtrationThe colorless precipitate is filtered off under suction
  3. washwashed with water
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-0cb5fe07597141849b590bf460fabdaf
Quelldatensatz
uspto-grants-1988_11
Patentnummer
US04785116

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