Hydrochloric Acid → 4-t-Butyl-2-(4-t-butylbenzoyl)benzoic acid

HRID 2241846Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2241846
[C:1]([C:5]1[CH:6]=[C:7]2[C:12](=[O:13])[O:11][C:9](=[O:10])[C:8]2=[CH:14][CH:15]=1)([CH3:4])([CH3:3])[CH3:2].[C:16]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)([CH3:19])([CH3:18])[CH3:17].[Cl-].[Al+3].[Cl-].[Cl-].Cl>ClC(Cl)C>[C:1]([C:5]1[CH:15]=[CH:14][C:8]([C:9]([OH:11])=[O:10])=[C:7]([C:12](=[O:13])[C:23]2[CH:24]=[CH:25][C:20]([C:16]([CH3:19])([CH3:18])[CH3:17])=[CH:21][CH:22]=2)[CH:6]=1)([CH3:4])([CH3:3])[CH3:2]

Komponenten

6

Edukt 4

HCID 313Hydrochloric AcidHCID 7366Tert-ButylbenzeneHCID 1229304-tert-Butylphthalic anhydrideHCID 6451240Aluminum(III) Chloride

Produkt 1

HCID 77302724-t-Butyl-2-(4-t-butylbenzoyl)benzoic acidAusbeute 64 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 63651,1-DichloroethaneLösungsmittel

Reaktionsbedingungen

Temperatur
0 °C

Versuchsvorschrift

Added into a 500 ml three-necked flask under the environment of argon were 4-t-butylphthalic anhydride 36 g (176 mmole), t-butylbenzene 27 g (200 mmole) and dichloroethane 100 ml. The mixture was cooled to 0° C. Aluminum chloride 56 g (420 mmole) was added gradually to them. After the addition, they were stirred at room temperature overnight. After the reaction, ice was added gradually followed by the addition of concentrated hydrochloric acid. After the precipitates were filtered, they were thoroughly washed to give the benzoic acid substance 32 g (yield 64%, white powder).

Aufarbeitung

  1. additionAdded into a 500 ml three-necked flask under the environment of argon
  2. additionAfter the addition, they
  3. customAfter the reaction, ice
  4. additionwas added gradually
  5. filtrationAfter the precipitates were filtered
  6. washthey were thoroughly washed

Quellen und Nachweise

ORD-Eintrag
ord-8044212375034425a9fa8f3f91130488
Quelldatensatz
uspto-grants-2010_03
Patentnummer
US07670506B1

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