Benzoyl Peroxide → Ethyl 2-Bromo-2-(3-chlorophenyl)acetate

HRID 224278Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 224278
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:8][C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH:5]=[CH:6][CH:7]=1.[Br:14]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:14][CH:8]([C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=1)[C:9]([O:11][CH2:12][CH3:13])=[O:10]

Komponenten

5

Edukt 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 8063366Ethyl 2-(3-chlorophenyl)acetate

Produkt 1

HCID 12717576Ethyl 2-Bromo-2-(3-chlorophenyl)acetate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 5943Carbon TetrachlorideLösungsmittel

Versuchsvorschrift

A 53.6 g portion of ethyl m-chlorophenylacetate (prepared by esterification of the corresponding acid), 51.5 g of N-bromosuccinimide and one gram of benzoyl peroxide in 1.25 liters of carbon tetrachloride is stirred with a Nichrome metal stirrer and refluxed for 20 hours. The mixture is cooled, filtered and concentrated to an orange oil. Vacuum distillation yields the product ethyl α-bromo-m-chlorophenylacetate.

Aufarbeitung

  1. temperaturerefluxed for 20 hours
  2. temperatureThe mixture is cooled
  3. filtrationfiltered
  4. concentrationconcentrated to an orange oil
  5. distillationVacuum distillation

Quellen und Nachweise

ORD-Eintrag
ord-368e9fb174c942b6b2dd3cf4367b3830
Quelldatensatz
uspto-grants-1980_11
Patentnummer
US04231935

Notizen zur Reaktion

Wird geladen…