[(Aminocarbonyl)hydrazono](phenyl)acetaldehyde → 6-Phenyl-1,2,4-triazin-3(2H)-one

HRID 2245930Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2245930
[NH2:1][C:2]([NH:4][N:5]=[C:6]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[CH:7]=O)=[O:3]>C(O)(=O)C>[C:9]1([C:6]2[CH:7]=[N:1][C:2](=[O:3])[NH:4][N:5]=2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Komponenten

3

Edukt 1

HCID 54444391[(Aminocarbonyl)hydrazono](phenyl)acetaldehyde

Produkt 1

HCID 112637836-Phenyl-1,2,4-triazin-3(2H)-oneAusbeute 90,1 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

[(Aminocarbonyl)hydrazono](phenyl)acetaldehyde (3.00 g, 0.0157 mol) in acetic acid (15.0 mL) was heated at 130° C. for 6 h. After cooling, the solvent was removed under reduced pressure. The residue was triturated with ether, filtered, washed with ether, and dried under high vacuum to give the desired product (2.45 g, 90.1%). Analytical LCMS: (M+H)+=174.0.

Aufarbeitung

  1. temperatureAfter cooling
  2. customthe solvent was removed under reduced pressure
  3. customThe residue was triturated with ether
  4. filtrationfiltered
  5. washwashed with ether
  6. customdried under high vacuum

Quellen und Nachweise

ORD-Eintrag
ord-c4086d089c624ad5801abddf5ee6eb32
Quelldatensatz
uspto-grants-2010_03
Patentnummer
US07683060B2

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