Malonic Acid → Nitropropanedioic acid

HRID 22467

Reaktionsgleichung

Reaktionsgleichung von HRID 22467
[C:1]([OH:7])(=[O:6])[CH2:2][C:3]([OH:5])=[O:4].[N+:8]([O-])([O:10]C(=O)C)=[O:9]>C(O)(=O)C.C(OC(=O)C)(=O)C>[N+:8]([CH:2]([C:1]([OH:7])=[O:6])[C:3]([OH:5])=[O:4])([O-:10])=[O:9]

Komponenten

4

Edukt 2

HCID 867Malonic AcidHCID 11557Acetyl nitrate

Produkt 1

HCID 19816496Nitropropanedioic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 21895370AcOH AcOAcLösungsmittel

Versuchsvorschrift

Nitration of malonic acid with acetyl nitrate in acetic acid/acetic anhydride was conducted to obtain nitromalonic acid. To the nitromalonic acid is added urea to obtain a condensation reaction mixture which is refluxed to form dilituric acid in situ. Various salts are separately prepared from the dilituric acid in situ using as cation sources potassium chloride, ammonia, and guanidinium chloride. The potassium diliturate salt, ammonium diliturate, guanidinium diliturate salts are each recovered and isolated by filtration.

Quellen und Nachweise

ORD-Eintrag
ord-1175029bb47c455caecd1dd090779881
Quelldatensatz
uspto-grants-1995_06
Patentnummer
US05428165

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