Bromine → 1-Bromo-1-(3-methanesulphonyl-phenyl)-propanone

HRID 2247398Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2247398
[CH3:1][S:2]([C:5]1[CH:6]=[C:7]([CH2:11][C:12](=[O:14])[CH3:13])[CH:8]=[CH:9][CH:10]=1)(=[O:4])=[O:3].[Br:15]Br>O1CCOCC1>[Br:15][CH:11]([C:7]1[CH:8]=[CH:9][CH:10]=[C:5]([S:2]([CH3:1])(=[O:3])=[O:4])[CH:6]=1)[C:12](=[O:14])[CH3:13]

Komponenten

4

Edukt 2

HCID 24408BromineHCID 665884811-(3-(Methylsulfonyl)phenyl)propan-2-one

Produkt 1

HCID 858616531-Bromo-1-(3-methanesulphonyl-phenyl)-propanone

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

A stirred solution of 1-(3-methanesulphonyl-phenyl)-propan-2-one (176b) (0.25 g, 1.18 mmol) in dioxane (10 ml) at 5° C. is treated with bromine (0.131 g, 0.82 mmol) added in two portions. The reaction is stirred and allowed to warm up to room temperature. The solvent is removed in vacuo to yield an orange oil of the titled compound.

Aufarbeitung

  1. additionadded in two portions
  2. customThe solvent is removed in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-0a5f01175050466a8c1e5d5efcf254ae
Quelldatensatz
uspto-grants-2010_03
Patentnummer
US07687637B2

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