Ethyl 3-(furan-2-yl)benzoate → [3-(2-Furyl)phenyl]methanol

HRID 2254439Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2254439
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[CH:7]=[C:8]([CH:14]=[CH:15][CH:16]=1)[C:9](OCC)=[O:10].[H-].[Al+3].[Li+].[H-].[H-].[H-]>C(OCC)C>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[CH:7]=[C:8]([CH:14]=[CH:15][CH:16]=1)[CH2:9][OH:10]

Komponenten

4

Edukt 2

HCID 19744763Ethyl 3-(furan-2-yl)benzoateHCID 21226445Aluminium lithium hydride

Produkt 1

HCID 11116545[3-(2-Furyl)phenyl]methanolAusbeute 83 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

Ethyl 3-(2-furyl)benzoate J. Chem. Soc., (B), 1971, 2305] was dissolved in 5 ml of anhydrous ethyl ether, and with stirring under ice cooling, 23 mg of lithium aluminum hydride was added. The mixture was stirred for 40 minutes. After the reaction, the reaction mixture was extracted by adding water and ethyl ether. The extract was worked up in a customary manner to give 170 mg (yield 83%) of 3-(2-furyl)benzyl alcohol.

Aufarbeitung

  1. stirringThe mixture was stirred for 40 minutes
  2. customAfter the reaction
  3. extractionthe reaction mixture was extracted
  4. additionby adding water and ethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-4554c789d62e45aebdcbd8fde12e3df5
Quelldatensatz
uspto-grants-1993_08
Patentnummer
US05234946

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