Iodoethane → HCID 22923495, Verbindung

HRID 2257753Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2257753
[CH2:1]([O:3][C:4]([N:6]1[CH2:11][CH2:10][CH:9]([N:12]2[C:21](=[O:22])[C:20]3[C:15](=[CH:16][CH:17]=[C:18]([CH3:23])[CH:19]=3)[NH:14][C:13]2=[O:24])[CH2:8][CH2:7]1)=[O:5])[CH3:2].[CH2:25](I)[CH3:26]>>[CH2:1]([O:3][C:4]([N:6]1[CH2:11][CH2:10][CH:9]([N:12]2[C:21](=[O:22])[C:20]3[C:15](=[CH:16][CH:17]=[C:18]([CH3:23])[CH:19]=3)[N:14]([CH2:25][CH3:26])[C:13]2=[O:24])[CH2:8][CH2:7]1)=[O:5])[CH3:2]

Komponenten

3

Edukt 2

HCID 6340IodoethaneHCID 218512463-(1-Ethoxycarbonyl-4-piperidinyl)-1,2,3,4-tetrahydro-6-methyl-2,4-dioxoquinazoline2×

Produkt 1

HCID 22923495HCID 22923495, VerbindungAusbeute 79 %

Versuchsvorschrift

The procedure similar to that described in Example 1 was repeated, except that 1.0 g (3.02 mmol) of 3-(1-ethoxycarbonyl-4-piperidinyl)-1,2,3,4-tetrahydro-6-methyl-2,4-dioxoquinazoline (Compound f) was used in place of Compound 24 and ethyl iodide was used in place of methyl iodide, whereby 855.0 mg (yield: 79%) of Compound b was obtained as white crystals.

Quellen und Nachweise

ORD-Eintrag
ord-beadcb6e96724a9b8a5533c57db9ed3f
Quelldatensatz
uspto-grants-1997_08
Patentnummer
US05658917

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