Glycidol → 3-(Octadecylamino)propane-1,2-diol

HRID 2260084

Reaktionsgleichung

Reaktionsgleichung von HRID 2260084
[CH2:1]([NH2:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH2:20]1[O:22][CH:21]1[CH2:23][OH:24]>C(O)C>[OH:22][CH:21]([CH2:23][OH:24])[CH2:20][NH:19][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

Komponenten

4

Edukt 2

HCID 11164GlycidolHCID 15793Octadecylamine

Produkt 1

HCID 1200883-(Octadecylamino)propane-1,2-diol

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

Octadecylamine (9.09 g, 0.034 mole) was dissolved in absolute ethanol. Glycidol (5.00 g, 0.068 mole) was added to the amine dropwise. The reaction solution was refluxed under nitrogen for 4 hours and then was stirred overnight at room temperature. A white solid was obtained (crude yield=10.8 g). The solid was recrystalized from hot hexane. (Yield=6.9 g).

Aufarbeitung

  1. temperatureThe reaction solution was refluxed under nitrogen for 4 hours
  2. customA white solid was obtained (crude yield=10.8 g)
  3. customThe solid was recrystalized from hot hexane

Quellen und Nachweise

ORD-Eintrag
ord-2093b14d28454a6cadc580b9c2ddb3ce
Quelldatensatz
uspto-grants-1995_12
Patentnummer
US05476671

Verknüpfte Notizen

Wird geladen…