Hydrochloric Acid → 2-(4-Amino-3-nitrobenzoyl)benzoic acid

HRID 2261924Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2261924
Cl[C:2]1[CH:18]=[CH:17][C:5]([C:6]([C:8]2[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=2[C:10]([OH:12])=[O:11])=[O:7])=[CH:4][C:3]=1[N+:19]([O-:21])=[O:20].Cl.[OH-].[NH4+:24]>>[NH2:24][C:2]1[CH:18]=[CH:17][C:5]([C:6]([C:8]2[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=2[C:10]([OH:12])=[O:11])=[O:7])=[CH:4][C:3]=1[N+:19]([O-:21])=[O:20]

Komponenten

4

Edukt 3

HCID 313Hydrochloric AcidHCID 14923Ammonium HydroxideHCID 665622-(4-Chloro-3-nitrobenzoyl)benzoic acid

Produkt 1

HCID 27975222-(4-Amino-3-nitrobenzoyl)benzoic acidAusbeute 98 %

Versuchsvorschrift

A solution of 2-(4-chloro-3-nitrobenzoyl)benzoic acid (5.0 g, 16.36 mmol) was heated to reflux in 28-30% aq. ammonium hydroxide (100 mL) for 18 h. The solution was cooled to room temperature followed by addition of 6N aq. hydrochloric acid until pH to 7. The precipitated yellow solid was collected by filtration and washed with water then dried in vacuo to provide 2-[(4-amino-3-nitrophenyl)carbonyl]benzoic acid (4.60 g, 98%). MS (EI) for C14H10N2O5: 288 (MH+).

Aufarbeitung

  1. filtrationThe precipitated yellow solid was collected by filtration
  2. washwashed with water
  3. customthen dried in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-106c24324f614c2690e00df2af337fbd
Quelldatensatz
uspto-grants-2010_12
Patentnummer
US07846959B2

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