Hexane → HCID 86618287, Verbindung
Reaktionsgleichung
[CH3:1][O:2][C:3]1[CH:13]=[CH:12][C:6]2[NH:7][CH2:8][CH2:9][CH2:10][CH2:11][C:5]=2[CH:4]=1.[F:14][C:15]([F:26])([F:25])[C:16]1[CH:17]=[C:18]([N:22]=[C:23]=[O:24])[CH:19]=[CH:20][CH:21]=1.CCCCCC>CCOCC>[F:14][C:15]([F:25])([F:26])[C:16]1[CH:17]=[C:18]([NH:22][C:23]([N:7]2[CH2:8][CH2:9][CH2:10][CH2:11][C:5]3[CH:4]=[C:3]([O:2][CH3:1])[CH:13]=[CH:12][C:6]2=3)=[O:24])[CH:19]=[CH:20][CH:21]=1Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A solution of 2.0 g (11.3 mMol) of 7-methoxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine [Monatsheft Chemie, 97 (1966),150] and 2.28 g (97%; 11.8 mMol) of 3-trifluoromethyl-phenyl-isocyanate in 20 ml ether is stirred for 30 min in a icebath. After addition of hexane, the mixture is concentrated partially in vacuo and the crystallized product filtered off: m.p.: 108° C.; MS: [M+1]+=365; Anal.: C,H,N,F.