HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2,5-Bis(trifluoromethyl)aniline → 2-[5-(2,5-Bis-trifluoromethyl-phenylamino)-3',5'-bis-trifluoromethyl-biphenyl-3-yl]-4-methyl-pentanoic acid methyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2,5-Bis(trifluoromethyl)aniline | HCID 719818 | — |
| Edukt | 4-Methyl-2-(5-trifluoromethanesulfonyloxy-3',5'-bis-trifluoromethyl-bi phenyl-3-yl)-pentanoic acid methyl ester | HCID 57754914 | — |
| Produkt | 2-[5-(2,5-Bis-trifluoromethyl-phenylamino)-3',5'-bis-trifluoromethyl-biphenyl-3-yl]-4-methyl-pentanoic acid methyl ester | HCID 57755031 | 39% |
Reaktionsschritte
The title compound was prepared in 39% yield from 4-methyl-2-(5-trifluoromethanesulfonyloxy-3′,5′-bis-trifluoromethyl-biphenyl-3-yl)-pentanoic acid methyl ester (prepared in Example 43, step (a)) and 2,5-bis-trifluoromethyl-aniline under the conditions described in Example 37, step (b).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07557244B2 |
| Quelldatensatz | uspto-grants-2009_07 |
| ORD ID | ord-954e1979797c4909819a8da2cd94a0b2 |
| Quellennotiz | uspto-grants-2009_07 |