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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 226546Erstellt: 25. Oktober 2026

2,5-Bis(trifluoromethyl)aniline → 2-[5-(2,5-Bis-trifluoromethyl-phenylamino)-3',5'-bis-trifluoromethyl-biphenyl-3-yl]-4-methyl-pentanoic acid methyl ester

https://huagongshe.com/reaction/226546

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2,5-Bis(trifluoromethyl)anilineHCID 719818—
Edukt4-Methyl-2-(5-trifluoromethanesulfonyloxy-3',5'-bis-trifluoromethyl-bi phenyl-3-yl)-pentanoic acid methyl esterHCID 57754914—
Produkt2-[5-(2,5-Bis-trifluoromethyl-phenylamino)-3',5'-bis-trifluoromethyl-biphenyl-3-yl]-4-methyl-pentanoic acid methyl esterHCID 5775503139%

Reaktionsschritte

The title compound was prepared in 39% yield from 4-methyl-2-(5-trifluoromethanesulfonyloxy-3′,5′-bis-trifluoromethyl-biphenyl-3-yl)-pentanoic acid methyl ester (prepared in Example 43, step (a)) and 2,5-bis-trifluoromethyl-aniline under the conditions described in Example 37, step (b).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07557244B2
Quelldatensatzuspto-grants-2009_07
ORD IDord-954e1979797c4909819a8da2cd94a0b2
Quellennotizuspto-grants-2009_07