HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(2,4-Dihydroxy-3-methylphenyl)ethan-1-one → 2-(3-((4-Acetyl-3-hydroxy-2-methylphenoxy)methyl)phenylthio) isonicotinonitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(2,4-Dihydroxy-3-methylphenyl)ethan-1-one | HCID 592139 | — |
| Edukt | 2-{[3-(Hydroxymethyl)phenyl]sulfanyl}pyridine-4-carbonitrile | HCID 57355460 | — |
| Produkt | 2-(3-((4-Acetyl-3-hydroxy-2-methylphenoxy)methyl)phenylthio) isonicotinonitrile | HCID 68537769 | 52% |
Reaktionsschritte
Using the method of Preparation 166 using 2-(3-(hydroxymethyl)phenylthio) isonicotinonitrile (1.46 g, 6.02 mmol) and 1-(2,4-dihydroxy-3-methylphenyl)ethanone (1.00 g, 6.02 mmol) affords the title compound (1.22 g, 52%). MS (APCI-neg) m/z (rel intensity): 389 (M−H, 100%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07858646B2 |
| Quelldatensatz | uspto-grants-2010_12 |
| ORD ID | ord-ebc5f64e2797474d8bf03e3017a24606 |
| Quellennotiz | uspto-grants-2010_12 |