Nicotinamide → 5469-10-3

HRID 2285764Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2285764
[CH2:1]([Br:10])[C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)=[O:3].[C:11]([NH2:19])(=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[N:14][CH:13]=1>CC(C)=O>[Br-:10].[C:11]([C:12]1[CH:13]=[N+:14]([CH2:1][C:2]([C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=2)=[O:3])[CH:15]=[CH:16][CH:17]=1)(=[O:18])[NH2:19]

Komponenten

4

Edukt 2

HCID 936NicotinamideHCID 6259Phenacyl bromide

Produkt 1

HCID 121189185469-10-3

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

17.5 g of phenacyl bromide was dissolved in 16 ml of acetone combined with a hot solution prepared by dissolving 10.73 g of nicotinamide in 24 ml of alcohol, and heated for 5 minutes on a steam bath. After cooling, crystals thus formed were collected by filtration and washed with alcohol and benzene to obtain 15.5 g of slightly yellow crystals (3-carbamoyl-1-phenacylpyridinium bromide).

Aufarbeitung

  1. customprepared
  2. temperatureheated for 5 minutes on a steam bath
  3. temperatureAfter cooling
  4. customcrystals thus formed
  5. filtrationwere collected by filtration
  6. washwashed with alcohol and benzene

Quellen und Nachweise

ORD-Eintrag
ord-cc3be0cc958e486dbbd9be832e012b66
Quelldatensatz
uspto-grants-1982_04
Patentnummer
US04324855

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