1,6-Dibromohexane → 4-(6-Bromohexyloxy)-4'-nitrobiphenyl

HRID 2291258

Reaktionsgleichung

Reaktionsgleichung von HRID 2291258
[K].[OH:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][C:12]([N+:15]([O-:17])=[O:16])=[CH:11][CH:10]=2)=[CH:5][CH:4]=1.[Br:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]Br.C1OCCOCCOCCOCCOCCOC1>C1(C)C=CC=CC=1>[Br:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[CH:14]=[CH:13][C:12]([N+:15]([O-:17])=[O:16])=[CH:11][CH:10]=2)=[CH:7][CH:8]=1

Komponenten

6

Edukt 4

HCID 123681,6-DibromohexaneHCID 2855718-Crown-6HCID 1380784-Hydroxy-4'-nitrobiphenylHCID 5462222Potassium

Produkt 1

HCID 200312344-(6-Bromohexyloxy)-4'-nitrobiphenyl

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

To 500 ml of toluene in a 100 ml round bottom flask, fitted with a condenser and magnetic stirrer, are added 7.6 g (0.03M) of the potassium salt of 4-hydroxy-4'-nitrobiphenyl, 36.6 g (0.15M) of 1,6-dibromohexane, and 0.5 g of 18-crown-6 ether. The mixture is refluxed for about 20 hours, and then filtered hot. The solvent is evaporated, and the residual crude product is recrystallized from hexane to provide purified product.

Aufarbeitung

  1. temperatureThe mixture is refluxed for about 20 hours
  2. filtrationfiltered hot
  3. customThe solvent is evaporated
  4. customthe residual crude product is recrystallized from hexane
  5. customto provide
  6. custompurified product

Quellen und Nachweise

ORD-Eintrag
ord-f360704a57c143c7a3c6b8dd3e9919a2
Quelldatensatz
uspto-grants-1989_01
Patentnummer
US04795664

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