N,N-dimethyl-2-nitrobenzamide → 2-Amino-N,N-dimethylbenzamide
Reaktionsgleichung
[CH3:1][N:2]([CH3:14])[C:3](=[O:13])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[N+:10]([O-])=O>[Pd].C(O)C>[NH2:10][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[C:3]([N:2]([CH3:14])[CH3:1])=[O:13]Komponenten
4
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
A mixture of N,N-dimethyl-2-nitrobenzamide (4.76 g, 24.5 mmol) and 10% palladium on carbon (470 mg) in 100 mL of ethanol was stirred under hydrogen at atmospheric pressure for approximately 12 hours. The mixture was filtered and concentrated to dryness to give 2-amino-N,N-dimethylbenzamide (4 g, 24.2 mmol), m.p. 53°-54° C.
Aufarbeitung
- filtrationThe mixture was filtered
- concentrationconcentrated to dryness
Quellen und Nachweise
- ORD-Eintrag
- ord-f6451c774b1749d49a417ccd75964742
- Quelldatensatz
- uspto-grants-1997_11
- Patentnummer
- US05688795
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