HCID 21473507, Verbindung → HCID 21473455, Verbindung
Reaktionsgleichung
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[N:10]1[CH2:15][CH2:14][N:13]([CH2:16][CH2:17][CH2:18][NH:19][C:20]2[CH:30]=[CH:29][C:28]([CH3:31])=[CH:27][C:21]=2[C:22]([N:24]([CH3:26])[CH3:25])=[O:23])[CH2:12][CH2:11]1)([O-])=O>[Pd].C(O)C>[NH2:1][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[N:10]1[CH2:15][CH2:14][N:13]([CH2:16][CH2:17][CH2:18][NH:19][C:20]2[CH:30]=[CH:29][C:28]([CH3:31])=[CH:27][C:21]=2[C:22]([N:24]([CH3:26])[CH3:25])=[O:23])[CH2:12][CH2:11]1Komponenten
4
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
A mixture of 2-{3-[4-(2-nitrophenyl)piperazin-1-yl]propylamino}-N,N,5-trimethylbenzamide (580 mg, 1.36 mmol), prepared as in Example 26, and 10% palladium on carbon (70 mg) in 15 mL of ethanol was added and stirred under hydrogen at room temperature for approximately 12 hours. The mixture was filtered and concentrated to give 2-{3-[4-(2-aminophenyl)piperazin-1-yl]propyl-amino}-N,N,5-trimethylbenzamide.