Hydrazine → 3-Phenylpropanehydrazide

HRID 230788

Reaktionsgleichung

Reaktionsgleichung von HRID 230788
[C:1]([O:11]C)(=O)/[CH:2]=[CH:3]/[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[NH2:13][NH2:14]>CO>[C:4]1([CH2:3][CH2:2][C:1]([NH:13][NH2:14])=[O:11])[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Komponenten

4

Edukt 2

HCID 9321HydrazineHCID 637520Methyl Cinnamate

Produkt 1

HCID 2493483-Phenylpropanehydrazide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

Methyl trans-cinnamate (1.0 g) and hydrazine (1.2 mL) were heated in methanol (25 mL) at 60° C. for 20 hours. The reaction solution was concentrated under reduced pressure, and the resulting residue was purified through silica gel column chromatography (ethyl acetate/methanol=95/5)to obtain a mixture of the entitled compound and an olefin-unreduced compound (2/1) (499 mg).

Aufarbeitung

  1. concentrationThe reaction solution was concentrated under reduced pressure
  2. customthe resulting residue was purified through silica gel column chromatography (ethyl acetate/methanol=95/5)to
  3. customobtain
  4. additiona mixture of the entitled compound

Quellen und Nachweise

ORD-Eintrag
ord-2e8e36378fc94ffc8d65a6a9eec7bda1
Quelldatensatz
uspto-grants-2009_07
Patentnummer
US07566781B2

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