Thionyl Chloride → HCID 14049831, Verbindung

HRID 232202Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 232202
O=[C:2]([CH2:16][CH2:17][C:18]([O-:20])=[O:19])[C:3]([O:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([N+:13]([O-:15])=[O:14])=[CH:9][CH:8]=1)=[O:4].S(Cl)([Cl:23])=O>ClCCCl>[Cl:23][C:2]1([C:3]([O:5][CH2:6][C:7]2[CH:8]=[CH:9][C:10]([N+:13]([O-:15])=[O:14])=[CH:11][CH:12]=2)=[O:4])[CH2:16][CH2:17][C:18](=[O:19])[O:20]1

Komponenten

4

Edukt 2

HCID 24386Thionyl ChlorideHCID 221664155-[(4-Nitrophenyl)methoxy]-4,5-dioxopentanoate

Produkt 1

HCID 14049831HCID 14049831, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 111,2-DichloroethaneLösungsmittel

Versuchsvorschrift

In 16 ml of 1,2-dichloroethane was dissolved 0.40 g of the Compound (1) obtained in Example 1. To the solution was added 0.88 ml of thionyl chloride. The mixture was heated for 10 hours under reflux. The solvent was evaporated off, and the residue was subjected to a silica gel column chromatography, followed by elution with hexane-ethyl acetate (3:1) to give 0.36 g of the subject Compound (15) as colorless oil.

Aufarbeitung

  1. temperatureThe mixture was heated for 10 hours
  2. temperatureunder reflux
  3. customThe solvent was evaporated off
  4. washfollowed by elution with hexane-ethyl acetate (3:1)

Quellen und Nachweise

ORD-Eintrag
ord-d0ae1d9eed84417eaaa8d23cb6753991
Quelldatensatz
uspto-grants-1989_07
Patentnummer
US04851422

Notizen zur Reaktion

Wird geladen…