Thionyl Chloride → HCID 20030930, Verbindung

HRID 232231Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 232231
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[C:10](=[O:24])[C:11]([O:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([N+:21]([O-:23])=[O:22])=[CH:17][CH:16]=1)=[O:12])([OH:3])=O.S(Cl)([Cl:27])=O>ClC(Cl)C>[Cl:27][C:10]1([C:11]([O:13][CH2:14][C:15]2[CH:16]=[CH:17][C:18]([N+:21]([O-:23])=[O:22])=[CH:19][CH:20]=2)=[O:12])[C:5]2[C:4](=[CH:9][CH:8]=[CH:7][CH:6]=2)[C:1](=[O:3])[O:24]1

Komponenten

4

Edukt 2

HCID 24386Thionyl ChlorideHCID 86743267HCID 86743267, Verbindung

Produkt 1

HCID 20030930HCID 20030930, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 63651,1-DichloroethaneLösungsmittel

Versuchsvorschrift

In 15 ml of dichloroethane was dissolved 580 mg of Compound (97), followed by addition of 0.58 ml of thionyl chloride. The mixture was heated for one hour under reflux. The solvent was evaporated off, and the residue was treated with isopropylether to give 500 mg of the subject Compound (98) as colorless crystals, m.p. 132°-134° C.

Aufarbeitung

  1. temperatureThe mixture was heated for one hour
  2. temperatureunder reflux
  3. customThe solvent was evaporated off
  4. additionthe residue was treated with isopropylether

Quellen und Nachweise

ORD-Eintrag
ord-89123cdad9c847ea8d5509cddc926a77
Quelldatensatz
uspto-grants-1989_07
Patentnummer
US04851422

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