3-Hydroxybenzaldehyde → 3-Ethoxybenzaldehyde
Reaktionsgleichung
[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH:5]=[O:6].[CH2:10](I)[CH3:11].C([O-])([O-])=O.[K+].[K+]>CC(C)=O>[CH2:10]([O:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH:5]=[O:6])[CH3:11]Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
3-Hydroxybenzaldehyde (3.0 g, 24.6 mmol), ethyl iodide (5.9 ml, 73.8 mmol) and K2CO3 (3.4 g, 24.6 mmol) in 50 ml of acetone was stirred at +40° C. for 6 h and at RT overnight. The mixture was filtered and evaporated. The product was purified by silica gel column chromatography (EtOAc/petroleum ether 15:100) to give 3-ethoxybenzaldehyde.
Aufarbeitung
- filtrationThe mixture was filtered
- customevaporated
- customThe product was purified by silica gel column chromatography (EtOAc/petroleum ether 15:100)
Quellen und Nachweise
- ORD-Eintrag
- ord-357c35243ea0405e86ab297315d2ce46
- Quelldatensatz
- uspto-grants-1997_01
- Patentnummer
- US05593993
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