Trityl chloride → 4-Iodo-1-(triphenylmethyl)-1H-pyrazole

HRID 23446

Reaktionsgleichung

Reaktionsgleichung von HRID 23446
[I:1][C:2]1[CH:3]=[N:4][NH:5][CH:6]=1.[C:7]1([C:13](Cl)([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.C(N(CC)CC)C>CN(C=O)C>[C:13]([N:4]1[CH:3]=[C:2]([I:1])[CH:6]=[N:5]1)([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)([C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1

Komponenten

5

Edukt 3

HCID 6456Trityl chlorideHCID 8471TriethylamineHCID 770224-Iodopyrazole

Produkt 1

HCID 153244794-Iodo-1-(triphenylmethyl)-1H-pyrazole

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

The title compound was prepared by combining 4-iodopyrazole (10 g, 52 mmol), triphenylmethyl chloride (14.4 g, 51.6 mmol), triethylamine (NEt3) (7.2 mL, 52 mmol), and DMF (80 mL). After stirring overnight, the mixture was poured onto ice water. The precipitated solid was collected and recrystallized to give the title compound as a solid, mp 193-194° C.

Aufarbeitung

  1. customThe title compound was prepared
  2. additionthe mixture was poured onto ice water
  3. customThe precipitated solid was collected
  4. customrecrystallized

Quellen und Nachweise

ORD-Eintrag
ord-d3ef2a74458c4b448cd736d864cc3c8b
Quelldatensatz
uspto-grants-2005_02
Patentnummer
US06852711B2

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